Description: Non-Invasive method for the diagnosis of adenocarcinomas or their precursor lesions in females by analyzing cells and preparing epithelial cells od a sample obtained from a rinse of the uterine cavity and optionally the fallopian tubes, and- performing analysis in said cells to determine an abnormality associated with ovarian or endometrial cancer, the abnormality being indicative of adenocarcinoma or their precursor lesions.